Restylane is intended to break down naturally in your body over a period of time. For most people, Restylane injections will last between 6-12 months. The amount of time that it takes to break down varies based on how the patients body reacts to the injection as different people will break down the Restylane at faster rates than others. It should be noted however that the shift back to your original look will not all occur at once after that period of time but rather will be a gradual process. For this reason, many people choose to have their procedure updated at various intervals throughout the year to keep up the same appearances.